SCHEMBL2886374

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25214135	0.85	APP (0.58)	APPMAOBMAOALMNAMMP13
	SCHEMBL17262129	0.83	APP (0.56)	APPMAOBMAOATSHRDAO
	SCHEMBL28625801	0.83	APP (0.56)	APPMAOBMAOALMNAMMP13
	SCHEMBL7956847	0.83	APP (0.56)	APPMAOBMAOALMNATSHR
	SCHEMBL3228582	0.81	APP (0.82)	APPMAOBMAOATSHRDAO
	SCHEMBL31294163	0.81	APP (0.57)	APPMAOBMAOALMNAMMP13
	SCHEMBL28585249	0.81	APP (0.54)	APPMAOBMAOATSHRDAO
	SCHEMBL2887792	0.80	SCN9A (0.52)	MAOBMAOALMNAALDH1A1RAB9A
	SCHEMBL28526426	0.78	APP (0.72)	APPMAOBMAOATSHRDAO
	SCHEMBL11883440	0.78	APP (0.54)	APPMAOBMAOALMNADAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.