SCHEMBL28864017

SCHEMBL28864017

Fc1cc(NBr)c(F)c(F)c1F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1556479 0.76
SCHEMBL4658413 0.74 ALDH1A1 (0.41) CES2CES1
SCHEMBL9592170 0.74
SCHEMBL6051815 0.74 CES2 (0.33) CES2CES1
SCHEMBL998478 0.74 CA1 (0.36)
SCHEMBL6284261 0.73 GRM4 (0.41) CES2CES1
Bromide SCHEMBL20984788 0.72 CA1 (0.35)
SCHEMBL7702552 0.69 CA1 (0.43) CES2CES1
SCHEMBL41646 0.69 CA1 (0.43) CES2CES1
SCHEMBL6283513 0.69 NPC1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115192577-A KRAS mutein inhibitors 北京加科思新药研发有限公司 2022-10-18 CN disclosed