SCHEMBL6284261

SCHEMBL6284261

Fc1cc(F)c(F)c(Nc2cc(F)c(F)c(F)c2F)c1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.41
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
MAPK14 Q16539 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28864017 0.73 CES2 (0.30) CES2CES1
SCHEMBL15702108 0.72 MAP2K1 (0.50)
SCHEMBL6284403 0.72 GRM4 (0.44) GRM4MAPK14
SCHEMBL24455459 0.71 CES2 (0.38) GRM4CES2CES1RAPGEF4
SCHEMBL1638888 0.71 CES2 (0.38) GRM4CES2CES1MAPK14RAPGEF4
SCHEMBL1556479 0.70
Bromide SCHEMBL20984571 0.70 CES2 (0.37) GRM4CES2CES1
Hydrochloric Acid SCHEMBL20984814 0.70 CES2 (0.37) GRM4CES2CES1
Hydrochloric Acid SCHEMBL30555121 0.70 CES2 (0.37) GRM4CES2CES1
SCHEMBL5052571 0.70 CES2 (0.37) GRM4CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1284626-C Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEM PATENTS INC (US) 2006-11-15 CN disclosed
US-6919291-B2 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-07-19 US disclosed
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2004-06-10 US disclosed
CN-1477995-A Fluorinated zwitterionic cocatalyst activators for olefin polymerization 埃克森美孚化学专利公司 2004-02-25 CN disclosed
EP-1349653-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-10-08 EP disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization FZD7, FOS, COG4 GRM4 2712/4885CES2 1566/4885CES1 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.