Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL27594600 | 0.98 | CYP3A4 (0.50) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzamide SCHEMBL27949318 | 0.92 | L3MBTL1 (0.43) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzoic Acid SCHEMBL27997762 | 0.89 | CES2 (0.47) | MAPTTSHRMEN1KMT2ACES2 | |
| Benzamide SCHEMBL28124928 | 0.86 | CYP3A4 (0.70) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzamide SCHEMBL27949308 | 0.86 | CYP3A4 (0.38) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzoic Acid Hydrazide SCHEMBL9425264 | 0.84 | NAAA (0.53) | POLBCES2CES1NAAACA2 | |
| Decane SCHEMBL28230778 | 0.84 | MAPT (0.67) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzamide SCHEMBL22117133 | 0.82 | CYP3A4 (0.70) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzamide SCHEMBL28708926 | 0.82 | POLB (0.53) | CYP3A4MAPTPOLBPARP1TSHR | |
| Biphenyl SCHEMBL1725384 | 0.81 | CA2 (0.47) | TDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232037-A | Preparation method of benzoyl sulfonamide-N-substituted benzamide compound | 郑州手性药物研究院有限公司 | 2022-10-25 | — | — | CN | disclosed |