Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226564 | 0.70 | — | — | |
| SCHEMBL22686267 | 0.67 | FDPS (0.36) | KDM4CALDH1A1PKMFDPS | |
| SCHEMBL22593336 | 0.67 | — | — | |
| SCHEMBL18884481 | 0.65 | — | — | |
| SCHEMBL6991521 | 0.63 | — | — | |
| SCHEMBL13090072 | 0.62 | KDM4C (0.39) | KDM4CKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL21600874 | 0.61 | GPR142 (0.43) | KDM4CALDH1A1 | |
| SCHEMBL17025004 | 0.61 | KDM4C (0.51) | KDM4CKDM4EALDH1A1PKM | |
| SCHEMBL1998771 | 0.61 | — | — | |
| SCHEMBL1369210 | 0.61 | ALDH1A1 (0.50) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503604-A | (4- alkyl -5- acyl group -2- thiazoles) hydazone derivative and its medical usage | 湖南大学 | 2018-09-07 | — | — | CN | disclosed |