SCHEMBL28864485

SCHEMBL28864485

O=C(C(=O)c1ccccc1-c1cc(-c2ccccc2)cs1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.41
CES1 P23141 5/20 0.41
HDAC6 Q9UBN7 1/20 0.40
MMP12 P39900 1/20 0.39
HSD17B1 P14061 3/20 0.38
HSD17B2 P37059 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PRKDC P78527 1/20 0.37
KMO O15229 1/20 0.37
BCAT2 O15382 1/20 0.37
PTGER1 P34995 3/20 0.36
PTGER4 P35408 3/20 0.36
PTGER3 P43115 3/20 0.36
PTGER2 P43116 3/20 0.36
ADORA1 P30542 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28913097 0.84 NPC1 (0.51) HDAC6HSD17B1HSD17B2NPC1RAB9A
Benzene SCHEMBL28343003 0.77 BCAT2 (0.55) CES2CES1NPC1RAB9ASMN1; SMN2
Biphenyl SCHEMBL28340553 0.77 BCAT2 (0.55) CES2CES1NPC1RAB9ASMN1; SMN2
SCHEMBL27676197 0.77 BCAT2 (0.59) CES2CES1SMN1; SMN2BCAT2
SCHEMBL30277841 0.77 BCAT2 (0.59) CES2CES1SMN1; SMN2BCAT2
SCHEMBL27905635 0.75 CES2 (0.47) CES2CES1
SCHEMBL29972427 0.75 CES2 (0.67) CES2CES1RAB9A
SCHEMBL14944580 0.74 HDAC6 (0.58) CES2CES1HDAC6MMP12KMO
SCHEMBL27556906 0.73 HSD17B1 (0.44) HDAC6HSD17B1HSD17B2PRKDCPTGER1
Hydrogen Sulfide SCHEMBL27747421 0.72 HSD17B1 (0.43) HDAC6HSD17B1HSD17B2PRKDCPTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843853-B Composition and method for manufacturing device using the same 东洋合成工业株式会社 2022-09-20 CN disclosed