Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.41 |
| ▸ | CCR1 | P32246 | 4/20 | 0.41 |
| ▸ | CCR8 | P51685 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717020 | 0.83 | CCR1 (0.42) | HSP90AA1CCR1CCR8KDM4ECCR5 | |
| Ammonia Solution, Strong SCHEMBL28864861 | 0.81 | CCR1 (0.41) | HSP90AA1CCR1CCR8KDM4ECCR5 | |
| SCHEMBL3715453 | 0.80 | GLO1 (0.52) | HSP90AA1CCR1CCR8KDM4ECCR5 | |
| SCHEMBL3712064 | 0.80 | KDM4E (0.43) | HSP90AA1CCR1CCR8KDM4ECCR5 | |
| SCHEMBL15217635 | 0.79 | KDM4E (0.53) | HSP90AA1HSP90AB1KDM4EMMP2MAPT | |
| SCHEMBL1148845 | 0.78 | HRH1 (0.44) | CYP3A4CYP2D6 | |
| SCHEMBL3585252 | 0.78 | PDE4A (0.46) | KDM4ELMNAMAPTTSHRHTT | |
| SCHEMBL9275208 | 0.77 | SLC40A1 (0.50) | HSP90AA1CCR1CCR8KDM4ECCR5 | |
| SCHEMBL15652298 | 0.77 | KDM4E (0.48) | HSP90AA1HSP90AB1CCR1CCR8KDM4E | |
| SCHEMBL28864698 | 0.75 | NPC1 (0.35) | CCR1CCR8KDM4ECCR5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312009-B | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | 上海医药集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |