Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 5/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712064 | 0.87 | KDM4E (0.43) | GLO1ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL1148845 | 0.81 | HRH1 (0.44) | CYP3A4CYP2D6 | |
| SCHEMBL3717020 | 0.80 | CCR1 (0.42) | GLO1KDM4ENPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28864802 | 0.80 | LOXL2 (0.42) | ADORA3ADORA2AADORA1KDM4ENPC1 | |
| Ammonia Solution, Strong SCHEMBL28864861 | 0.79 | CCR1 (0.41) | GLO1KDM4ENPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3585252 | 0.78 | PDE4A (0.46) | KDM4EL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL25911521 | 0.77 | CYP3A4 (0.55) | KDM4ENPC1L3MBTL1PDE4APDE4B | |
| SCHEMBL22411254 | 0.77 | GLO1 (0.38) | GLO1ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL9275208 | 0.75 | SLC40A1 (0.50) | KDM4ENPC1L3MBTL1SMN1; SMN2SLC40A1 | |
| SCHEMBL25354572 | 0.71 | DAO (0.57) | KDM4ENPC1SMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |