Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Formic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869690 | 0.90 | MAPT (0.44) | MAPTALDH1A1HSD17B10TRPA1ATM | |
| SCHEMBL14919249 | 0.75 | MAPT (0.41) | MAPTALDH1A1TSHRGAAPOLB | |
| SCHEMBL30876196 | 0.73 | MAPT (0.40) | MAPTALDH1A1TSHRGAAPOLB | |
| SCHEMBL2253699 | 0.73 | MAPT (0.40) | MAPTALDH1A1TSHRGAAPOLB | |
| Formic Acid SCHEMBL28834551 | 0.73 | ACHE (0.40) | MAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL23173388 | 0.73 | TRPA1 (0.38) | MAPTALDH1A1HSD17B10TRPA1ATM | |
| SCHEMBL20083841 | 0.66 | TRPA1 (0.41) | MAPTALDH1A1TRPA1ATMSMN1; SMN2 | |
| SCHEMBL4531060 | 0.66 | MAPT (0.39) | MAPTALDH1A1HSD17B10TRPA1ATM | |
| SCHEMBL11765858 | 0.65 | MAPT (0.39) | MAPTALDH1A1HSD17B10TRPA1ATM | |
| SCHEMBL28921705 | 0.65 | ALDH1A1 (0.42) | MAPTALDH1A1HSD17B10TRPA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220413-B | Method for producing 4-hydroxybutyl acrylate | 大阪有机化学工业株式会社 | 2018-12-04 | — | — | CN | disclosed |