Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910896 | 0.79 | MEN1 (0.50) | MEN1KMT2ABLMCASP3CASP6 | |
| SCHEMBL3425376 | 0.78 | GLO1 (0.56) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL18788338 | 0.76 | CCR1 (0.51) | MEN1KMT2ATDP1L3MBTL1SLC40A1 | |
| SCHEMBL6589447 | 0.74 | TRIM24 (0.52) | MEN1KMT2ATDP1L3MBTL1KDR | |
| SCHEMBL31565225 | 0.73 | TDP1 (0.53) | MEN1KMT2ABLMCASP3CASP6 | |
| SCHEMBL4466489 | 0.73 | SLC40A1 (0.74) | MEN1KMT2ATDP1POLBSLC40A1 | |
| SCHEMBL14345508 | 0.72 | SLC40A1 (0.43) | MEN1KMT2ATDP1L3MBTL1POLB | |
| SCHEMBL23645096 | 0.72 | TMEM97 (0.46) | MEN1KMT2ABLMCASP3CASP6 | |
| SCHEMBL416258 | 0.70 | MEN1 (0.73) | MEN1KMT2ATDP1POLBSLC40A1 | |
| SCHEMBL15961561 | 0.70 | MMP2 (0.56) | TDP1HTTALOX15TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884061-A | 1,2,4- triazine -3- amine derivant, preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2018-11-23 | — | — | CN | disclosed |