SCHEMBL28867152

SCHEMBL28867152

C=CCc1cccc(N(Cc2ccccc2)c2ccccc2)c1CC=C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
NR3C2 P08235 1/20 0.35
GAA P10253 1/20 0.34
CNR2 P34972 1/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
TSHR P16473 1/20 0.33
KCNA3 P22001 1/20 0.33
KDM4E B2RXH2 1/20 0.32
AURKA O14965 1/20 0.32
DAPK3 O43293 1/20 0.32
MAP4K4 O95819 1/20 0.32
RET P07949 1/20 0.32
IGF1R P08069 1/20 0.32
MET P08581 1/20 0.32
PIM1 P11309 1/20 0.32
LTK P29376 1/20 0.32
KDR P35968 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28867129 0.81 GABRA1 (0.40) GABRA1GABRB2KDM4EAURKADAPK3
SCHEMBL4104054 0.76 GABRA1 (0.46) GABRA1GABRB2GAAKDM4EMEN1
SCHEMBL29236886 0.73 ESR1 (0.33) GABRA1GABRB2
SCHEMBL4058078 0.73 PTPN1 (0.42) NR3C2HDAC1HDAC8HDAC6TSHR
SCHEMBL84249 0.71 GABRA1 (0.38) GABRA1GABRB2ALDH1A1LMNA
SCHEMBL28024187 0.71 NPSR1 (0.41) GABRA1GABRB2KDM4EMEN1KMT2A
SCHEMBL18136 0.71 GABRA1 (0.56) GABRA1GABRB2GAAKDM4EAURKA
SCHEMBL3675862 0.71 GABRA1 (0.40) GABRA1GABRB2KDM4EAURKADAPK3
SCHEMBL4189715 0.71 GABRA1 (0.40) GABRA1GABRB2KDM4EAURKADAPK3
SCHEMBL9631883 0.69 GABRA1 (0.43) GABRA1GABRB2TSHRKDM4ECYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115216357-A High-temperature-resistant lubricating oil antioxidant and preparation method and application thereof 上海石化西尼尔化工科技有限公司 2022-10-21 CN disclosed