SCHEMBL3675862

SCHEMBL3675862

C=CCc1ccccc1N(c1ccccc1)c1ccccc1CC=C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.40
GABRB2 P47870 2/20 0.40
ADRA2B P18089 6/20 0.34
ADRA2C P18825 6/20 0.34
ADRA2A P08913 5/20 0.34
HTR1A P08908 3/20 0.34
NISCH Q9Y2I1 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
AURKA O14965 1/20 0.32
DAPK3 O43293 1/20 0.32
MAP4K4 O95819 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4189715 0.96 GABRA1 (0.40) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL1349623 0.92 ALDH1A1 (0.36) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL254011 0.90 GABRA1 (0.36) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL11388986 0.89 GABRA1 (0.38) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL9659364 0.89 GABRA1 (0.42) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL4565154 0.87 CYP3A4 (0.52) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL28867129 0.82 GABRA1 (0.40) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL8210128 0.82 CYP3A4 (0.42) GABRA1GABRB2KDM4EALDH1A1CYP1A2
SCHEMBL84249 0.81 GABRA1 (0.38) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL28247859 0.81 GABRA1 (0.38) GABRA1GABRB2ADRA2BADRA2CADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174961-B1 SYNDIOTACTIC PROPYLENE POLYMERS AND LUBRICATING OILS COMPRISING THE SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-11-20 EP claimed
EP-2516598-B1 PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS EXXONMOBIL CHEM PATENTS INC (US) 2016-06-29 EP claimed
EP-2173779-A2 PROCESS TO PRODUCE POLYALPHAOLEFINS ExxonMobil Chemical Patents Inc. (US) 2010-04-14 EP claimed
EP-2041194-A2 PROCESS TO PRODUCE HIGH VISCOSITY FLUIDS ExxonMobil Chemical Patents Inc. (US) 2009-04-01 EP claimed
US-20090036725-A1 Process To Produce Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. 2009-02-05 US claimed
WO-2009017953-A2 PROCESS TO PRODUCE POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENT INC. (US) 2009-02-05 WO claimed
US-20080177121-A1 Process to produce high viscosity fluids EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-24 US claimed
WO-2008010865-A2 PROCESS TO PRODUCE HIGH VISCOSITY FLUIDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-01-24 WO claimed
EP-2173779-A2 PROCESS TO PRODUCE POLYALPHAOLEFINS ExxonMobil Chemical Patents Inc. (US) 2010-04-14 EP disclosed
EP-2041194-A2 PROCESS TO PRODUCE HIGH VISCOSITY FLUIDS ExxonMobil Chemical Patents Inc. (US) 2009-04-01 EP disclosed
US-20090036725-A1 Process To Produce Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. 2009-02-05 US disclosed
WO-2009017953-A2 PROCESS TO PRODUCE POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENT INC. (US) 2009-02-05 WO disclosed
US-20080177121-A1 Process to produce high viscosity fluids EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-24 US disclosed
WO-2008010865-A2 PROCESS TO PRODUCE HIGH VISCOSITY FLUIDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036725-A1 Process To Produce Polyalphaolefins KCNMA1, F10, AP2A1 GABRA1 826/4885GABRB2 1317/4885ADRA2B 3294/4885
US-20080177121-A1 Process to produce high viscosity fluids SCO2, POLI, TAOK1 GABRA1 3815/4885GABRB2 4333/4885ADRA2B 3829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.