Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4104054 | 0.88 | GABRA1 (0.46) | GABRA1GABRB2AKR1B1ADRA2BADRA2C | |
| SCHEMBL4189715 | 0.86 | GABRA1 (0.40) | GABRA1GABRB2AURKADAPK3MAP4K4 | |
| SCHEMBL3675862 | 0.82 | GABRA1 (0.40) | GABRA1GABRB2AURKADAPK3MAP4K4 | |
| SCHEMBL28867152 | 0.81 | GABRA1 (0.36) | GABRA1GABRB2AURKADAPK3MAP4K4 | |
| SCHEMBL254011 | 0.80 | GABRA1 (0.36) | GABRA1GABRB2AURKADAPK3MAP4K4 | |
| SCHEMBL4565154 | 0.78 | CYP3A4 (0.52) | GABRA1GABRB2ADRA2BADRA2CADRA2A | |
| SCHEMBL9659364 | 0.76 | GABRA1 (0.42) | GABRA1GABRB2AURKADAPK3MAP4K4 | |
| SCHEMBL1349623 | 0.75 | ALDH1A1 (0.36) | GABRA1GABRB2AURKADAPK3MAP4K4 | |
| SCHEMBL18136 | 0.75 | GABRA1 (0.56) | GABRA1GABRB2AURKADAPK3MAP4K4 | |
| SCHEMBL29093464 | 0.73 | GABRA1 (0.40) | GABRA1GABRB2AKR1B1ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115216357-A | High-temperature-resistant lubricating oil antioxidant and preparation method and application thereof | 上海石化西尼尔化工科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-115216357-A | High-temperature-resistant lubricating oil antioxidant and preparation method and application thereof | 上海石化西尼尔化工科技有限公司 | 2022-10-21 | — | — | CN | disclosed |