Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932397 | 0.81 | ALDH1A1 (0.38) | MEN1GAAKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL23536364 | 0.81 | ALDH1A1 (0.38) | MEN1GAAKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL23536058 | 0.78 | CYP2A13 (0.34) | MEN1USP2GAAKMT2AHRH4 | |
| SCHEMBL23535973 | 0.78 | CYP2A13 (0.34) | MEN1USP2GAAKMT2AHRH4 | |
| SCHEMBL23536077 | 0.76 | BPTF (0.35) | USP2GAASMN1; SMN2 | |
| SCHEMBL28867430 | 0.75 | MCOLN2 (0.34) | GAAKMT2A | |
| SCHEMBL23536167 | 0.74 | MEN1 (0.34) | MEN1USP2GAAKMT2AHRH4 | |
| SCHEMBL14804508 | 0.72 | BPTF (0.38) | MEN1USP2GAAKMT2A | |
| SCHEMBL23536010 | 0.71 | KDM1A (0.34) | NPC1RAB9A | |
| SCHEMBL23536324 | 0.71 | KDM1A (0.34) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |