Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009362 | 0.78 | RBBP9 (0.49) | LMNAPOLBCTSAALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL7013057 | 0.74 | CTSA (0.38) | LMNACTSAALDH1A1NPC1RAB9A | |
| SCHEMBL6009307 | 0.74 | ALDH1A1 (0.44) | HSD17B10CTSAALDH1A1NPC1RAB9A | |
| SCHEMBL8366794 | 0.72 | ALDH1A1 (0.39) | LMNACTSAALDH1A1NPC1RAB9A | |
| SCHEMBL29291637 | 0.69 | CA12 (0.53) | CTSAALDH1A1KMT2ATSHR | |
| SCHEMBL507287 | 0.67 | ALDH1A1 (0.35) | LMNAHSD17B10CTSAALDH1A1NPC1 | |
| SCHEMBL2653105 | 0.66 | KDM4E (0.36) | LMNAHSD17B10CTSAALDH1A1NPC1 | |
| SCHEMBL22474224 | 0.65 | CTSA (0.47) | CTSAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27769601 | 0.65 | CTSA (0.61) | CTSA | |
| SCHEMBL909602 | 0.65 | ALDH1A1 (0.44) | LMNACTSAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071504-A | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2018-12-21 | — | — | CN | disclosed |