SCHEMBL6009307

SCHEMBL6009307

CC(=O)OC(C)c1nccs1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
CTSA P10619 9/20 0.38
RAB9A P51151 2/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 1/20 0.35
ACACB O00763 1/20 0.35
NPC1 O15118 1/20 0.35
MAPKAPK2 P49137 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8366794 0.84 ALDH1A1 (0.39) ALDH1A1CTSARAB9ANPC1MAPKAPK2
Ammonia Solution, Strong SCHEMBL7013057 0.83 CTSA (0.38) ALDH1A1CTSARAB9ATSHRNPC1
SCHEMBL31079263 0.78 ALDH1A1 (0.41) ALDH1A1CTSARAB9AHSD17B10
SCHEMBL6009362 0.78 RBBP9 (0.49) ALDH1A1CTSARAB9ATSHRNPC1
SCHEMBL29291637 0.77 CA12 (0.53) ALDH1A1CTSATSHR
SCHEMBL2653105 0.76 KDM4E (0.36) ALDH1A1CTSARAB9AHSD17B10TSHR
SCHEMBL11983388 0.76 ALDH1A1 (0.48) ALDH1A1CTSATSHRACACBMAPKAPK2
SCHEMBL3311139 0.75
SCHEMBL28300435 0.74 FDPS (0.45) ALDH1A1CTSARAB9ATSHRACACB
SCHEMBL28867928 0.74 LMNA (0.44) ALDH1A1CTSARAB9AHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4272831-A2 DIAZABICYCLOOCTANONES AS INHIBITORS OF SERINE BETA-LACTAMASES Antabio SAS (FR) 2023-11-08 EP disclosed
CN-108659974-A A kind of bathroom peculiar-smell-removal detergent of -5- of methyl containing 4- Acetoxyethyls-thiazole 枣庄九星生物科技有限公司 2018-10-16 CN disclosed
CN-105713015-B A kind of imidazoheterocycles azo derivative and its preparation method and application 华南农业大学 2018-07-06 CN disclosed
CN-105713015-A Imidazo heterocyclic azo derivative and preparation method and application thereof 华南农业大学 2016-06-29 CN disclosed
EP-1292573-B1 SUBSTITUTED THIOACETAMIDES CEPHALON INC (US) 2010-12-29 EP disclosed
EP-2186803-A2 Substituted thioacetamides CEPHALON, INC. (US) 2010-05-19 EP disclosed
US-20080027228-A1 Substituted thioacetamides CEPHALON, INC. (US) 2008-01-31 US disclosed
US-7268132-B2 Thio substituted with a hetero multiring group; sleepiness, promotion of wakefulness, Parkinson's disease, cerebral ischemia, stroke, sleep apneas, eating disorders, stimulation of appetite and weight gain, attention deficit hyperactivity disorder CEPHALON, INC. (US) 2007-09-11 US disclosed
US-RE39575-E1 Substituted thioacetamides CEPHALON, INC. (US) 2007-04-17 US disclosed
US-7022721-B1 Method and composition for rejuvenating cells, tissues, organs, hair and nails ULRICH PETER C 2006-04-04 US disclosed
EP-1368029-A4 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS LLC (US) 2006-02-15 EP disclosed
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails ULRICH PETER C 2005-11-03 US disclosed
US-6777557-B2 Method and composition for rejuvenating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2004-08-17 US disclosed
EP-1368029-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS Farrington Pharmaceuticals, LLC (US) 2003-12-10 EP disclosed
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2002-12-12 US disclosed
WO-2002062301-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS, LLC (US) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027228-A1 Substituted thioacetamides TST, TTR, TBCA ALDH1A1 763/4885CTSA 1708/4885RAB9A 3498/4885
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 ALDH1A1 3396/4885CTSA 2635/4885RAB9A 1317/4885
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 ALDH1A1 3396/4885CTSA 2635/4885RAB9A 1317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.