SCHEMBL6009362

SCHEMBL6009362

CC(OC(=O)c1ccccc1)c1nccs1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RBBP9 O75884 1/20 0.49
NPC1 O15118 4/20 0.44
RAB9A P51151 4/20 0.44
TP53 P04637 2/20 0.44
TSHR P16473 2/20 0.44
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
HSPA5 P11021 1/20 0.42
HSPA9 P38646 1/20 0.42
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HTT P42858 1/20 0.41
CTSA P10619 4/20 0.41
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40
MEN1 O00255 1/20 0.40
HPGD P15428 1/20 0.40
SCD O00767 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29291637 0.87 CA12 (0.53) RBBP9TSHRPDCD1CD274ALDH1A1
Ammonia Solution, Strong SCHEMBL7013057 0.78 CTSA (0.38) NPC1RAB9ATSHRLMNAALDH1A1
SCHEMBL28867928 0.78 LMNA (0.44) NPC1RAB9ATSHRLMNASMN1; SMN2
SCHEMBL6009307 0.78 ALDH1A1 (0.44) NPC1RAB9ATSHRALDH1A1CTSA
SCHEMBL8366794 0.76 ALDH1A1 (0.39) NPC1RAB9ALMNAALDH1A1CTSA
SCHEMBL27768743 0.74 TSHR (0.47) NPC1RAB9ATP53TSHRPDCD1
SCHEMBL21261781 0.73 TSHR (0.53) NPC1RAB9ATP53TSHRPDCD1
SCHEMBL18328175 0.72 TSHR (0.57) NPC1RAB9ATP53TSHRPDCD1
SCHEMBL28159387 0.72 TSHR (0.57) NPC1RAB9ATP53TSHRPDCD1
SCHEMBL213819 0.72 TSHR (0.57) NPC1RAB9ATP53TSHRPDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7022721-B1 Method and composition for rejuvenating cells, tissues, organs, hair and nails ULRICH PETER C 2006-04-04 US disclosed
EP-1368029-A4 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS LLC (US) 2006-02-15 EP disclosed
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails ULRICH PETER C 2005-11-03 US disclosed
US-6777557-B2 Method and composition for rejuvenating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2004-08-17 US disclosed
EP-1368029-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS Farrington Pharmaceuticals, LLC (US) 2003-12-10 EP disclosed
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2002-12-12 US disclosed
WO-2002062301-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS, LLC (US) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 RBBP9 3678/4885NPC1 3338/4885RAB9A 1317/4885
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 RBBP9 3678/4885NPC1 3338/4885RAB9A 1317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.