SCHEMBL28867968

SCHEMBL28867968

CCCc1nccn1C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
PARP1 P09874 1/20 0.37
ALPG P10696 2/20 0.35
PLAA Q9Y263 1/20 0.35
ALPL P05186 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4256418 0.90 AGTR1 (0.41) PARP1ALDH1A1POLBKMT2AKDM4E
SCHEMBL28236700 0.87 TLR7 (0.40) ALDH1A1POLBKMT2AKDM4ELMNA
SCHEMBL28151261 0.85 ALPG (0.40) PDE4APDE4BPDE4CPDE4DPARP1
SCHEMBL2407748 0.81 LPO (0.44) PDE4APDE4BPDE4CPDE4DSMN1; SMN2
SCHEMBL1978411 0.77 AGTR1 (0.44) ALDH1A1POLBKMT2AKDM4ELMNA
SCHEMBL31647881 0.76 PARP1 (0.36) PARP1
SCHEMBL19468371 0.75 ALDH1A1 (0.33) PDE4APDE4BPDE4CPDE4DALPG
SCHEMBL28701458 0.75 FDPS (0.39) ALPGPLAAALPLSMN1; SMN2ALDH1A1
SCHEMBL18686228 0.75 AGTR1 (0.40) ALDH1A1POLBKMT2ALMNATSHR
SCHEMBL729229 0.75 AGTR1 (0.40) ALDH1A1POLBKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997214-A It is happy to cut down for Buddhist nun's intermediate and its preparation and the happy preparation cut down for Buddhist nun 成都地奥制药集团有限公司 2018-12-14 CN claimed