Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568399 | 0.93 | HPGD (0.32) | DGAT1CTSK | |
| SCHEMBL569888 | 0.76 | DGAT1 (0.31) | DGAT1CTSK | |
| SCHEMBL6320796 | 0.74 | BTK (0.31) | DGAT1 | |
| SCHEMBL14896297 | 0.73 | DGAT1 (0.32) | DGAT1CTSKUSP2SMN1; SMN2 | |
| SCHEMBL2064367 | 0.73 | HPGD (0.33) | DGAT1CTSKUSP2SMN1; SMN2 | |
| SCHEMBL7477261 | 0.72 | CTSK (0.32) | CTSK | |
| SCHEMBL2785917 | 0.71 | DGAT1 (0.31) | DGAT1CTSK | |
| SCHEMBL6608329 | 0.71 | HPGD (0.32) | DGAT1CTSK | |
| SCHEMBL5421441 | 0.70 | HPGD (0.31) | DGAT1 | |
| SCHEMBL2434403 | 0.70 | BTK (0.31) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892582-B | Azetidine as the mek inhibitor for treating proliferative disease | 埃克塞利希斯股份有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-109053523-A | Azetidine as the mek inhibitor for treating proliferative disease | 埃克塞利希斯股份有限公司 | 2018-12-21 | — | — | CN | disclosed |