Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880847 | 0.78 | CDK5 (0.38) | HCAR3ALDH1A1HSD17B10GAAKDM4E | |
| SCHEMBL6880852 | 0.75 | TTR (0.39) | ALDH1A1KDM4EMAPTKMT2ASRD5A2 | |
| SCHEMBL149814 | 0.69 | GFER (0.37) | ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10170781 | 0.66 | SLC6A4 (0.50) | ALDH1A1HSD17B10GAAKMOKDM4E | |
| SCHEMBL11169652 | 0.66 | SLC6A4 (0.50) | ALDH1A1HSD17B10GAAKMOKDM4E | |
| SCHEMBL28170978 | 0.64 | CAMKK2 (0.52) | KMOKDM4E | |
| SCHEMBL14273035 | 0.64 | GAA (0.52) | HCAR3ALDH1A1HSD17B10GAAKMO | |
| SCHEMBL12365276 | 0.64 | IGF1R (0.60) | ALDH1A1GAAKMOKDM4EMAPT | |
| SCHEMBL10923648 | 0.64 | ALDH1A1 (0.46) | ALDH1A1KMOKDM4EMAPTKMT2A | |
| SCHEMBL448284 | 0.63 | KMO (0.54) | KMOSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-A | Carbazole amide derivatives or its salt and its preparation method and application | 复旦大学 | 2019-01-15 | — | — | CN | disclosed |