Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.85 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL23672268 | 0.97 | CA4 (0.90) | CA4CASP1FAHD1 | |
| Citric Acid SCHEMBL28111939 | 0.97 | CA4 (0.90) | CA4CASP1 | |
| Citric Acid SCHEMBL27616111 | 0.97 | CA4 (0.90) | CA4CASP1FAHD1 | |
| Citric Acid SCHEMBL1650869 | 0.97 | CA4 (0.90) | CA4CASP1FAHD1 | |
| Citric Acid SCHEMBL8761101 | 0.97 | CA4 (0.90) | CA4CASP1FAHD1 | |
| Citric Acid SCHEMBL372318 | 0.95 | CA4 (0.84) | CA4CASP1FAHD1 | |
| Citric Acid SCHEMBL5163322 | 0.95 | CA4 (0.94) | CA4CASP1FAHD1 | |
| Citric Acid SCHEMBL6690080 | 0.95 | CA4 (0.94) | CA4CASP1FAHD1 | |
| Citric Acid SCHEMBL20917176 | 0.95 | CA4 (0.94) | CA4CASP1FAHD1 | |
| Citric Acid SCHEMBL372670 | 0.95 | CA4 (0.94) | CA4CASP1FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476558-A | Light foamed cement, cement board and manufacturing method thereof | 美国石膏公司 | 2019-03-15 | — | — | CN | disclosed |