Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | UBE2T | Q9NPD8 | 2/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.37 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17101820 | 0.78 | NNMT (0.45) | F7F3 | |
| SCHEMBL12249675 | 0.74 | PRSS1 (0.47) | PRSS1PRSS2PRSS3UBE2TTMPRSS2 | |
| SCHEMBL17984663 | 0.72 | HDAC1 (0.46) | PRSS1PRSS2PRSS3UBE2TC1S | |
| SCHEMBL28275926 | 0.72 | LMNA (0.44) | PRSS1PRSS2PRSS3UBE2TC1S | |
| SCHEMBL186656 | 0.71 | ALDH1A1 (0.52) | — | |
| SCHEMBL14095724 | 0.71 | KMT2A (0.37) | — | |
| SCHEMBL24144415 | 0.70 | NNMT (0.40) | PRSS1PRSS2PRSS3UBE2TC1S | |
| SCHEMBL4132044 | 0.70 | MAPT (0.37) | PKM | |
| SCHEMBL22167186 | 0.70 | UBE2T (0.37) | PRSS1PRSS2PRSS3UBE2TC1S | |
| SCHEMBL29337499 | 0.70 | ALDH1A1 (0.55) | PRSS1PRSS2PRSS3UBE2TC1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476664-A | New compound as autotaxin inhibitors and the pharmaceutical composition comprising it | 乐高化学生物科学股份有限公司 | 2019-03-15 | — | — | CN | disclosed |