Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | UBE2T | Q9NPD8 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.37 |
| ▸ | C1S | P09871 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 3/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MASP2 | O00187 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4764392 | 0.78 | NNMT (0.58) | NNMTMAP4K4HCAR3LMNA | |
| SCHEMBL28275926 | 0.72 | LMNA (0.44) | UBE2TPRSS1PRSS2PRSS3C1S | |
| SCHEMBL17984663 | 0.72 | HDAC1 (0.46) | NNMTUBE2TPRSS1PRSS2PRSS3 | |
| SCHEMBL186007 | 0.71 | HCAR3 (0.57) | NNMTGRM5HCAR3 | |
| SCHEMBL10588749 | 0.71 | HCAR3 (0.42) | NNMTMAP4K4GRM5HCAR3 | |
| SCHEMBL29337499 | 0.70 | ALDH1A1 (0.55) | GRM5UBE2TPRSS1PRSS2PRSS3 | |
| SCHEMBL22167186 | 0.70 | UBE2T (0.37) | UBE2TPRSS1PRSS2PRSS3C1S | |
| SCHEMBL16771926 | 0.70 | BAZ2B (0.47) | NNMTGRM5HCAR3 | |
| SCHEMBL24143953 | 0.70 | UBE2T (0.37) | UBE2TPRSS1PRSS2PRSS3C1S | |
| SCHEMBL28869347 | 0.70 | PRSS1 (0.42) | UBE2TPRSS1PRSS2PRSS3C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | UNIMATEC CO., LTD. (JP) | 2024-07-23 | — | — | US | disclosed |
| US-20210403455-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND METHOD FOR MANUFACTURING THE SAME | UNIMATEC CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | CNOT1, NUDT1, XRN2 | NNMT 474/4885MAP4K4 2891/4885GRM5 3601/4885 |
| US-20210403455-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND METHOD FOR MANUFACTURING THE SAME | CNOT1, NUDT1, XRN2 | NNMT 474/4885MAP4K4 2891/4885GRM5 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.