Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GOT1 | P17174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877249 | 0.80 | KIF11 (0.44) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL27973870 | 0.80 | KMT2A (0.52) | CYP11B1CYP11B2MAPTKDRKDM4E | |
| SCHEMBL28877285 | 0.78 | EGFR (0.55) | MAPTKDRKDM4ENPC1ALDH1A1 | |
| SCHEMBL28276004 | 0.78 | IP6K1 (0.36) | ACP1SCN5A | |
| SCHEMBL29816494 | 0.77 | KDM4E (0.48) | PDE10AMAPTKDRKDM4ENPC1 | |
| SCHEMBL1268508 | 0.77 | KDM4E (0.48) | PDE10AMAPTKDRKDM4ENPC1 | |
| SCHEMBL28657632 | 0.76 | KDM4E (0.47) | PDE10AMAPTKDRKDM4ENPC1 | |
| SCHEMBL29118706 | 0.75 | ACP1 (0.48) | ACP1SCN5ACYP11B1CYP11B2PDE10A | |
| SCHEMBL30656055 | 0.74 | CYP1A2 (0.43) | PDE10AMAPTKDRKDM4ENPC1 | |
| SCHEMBL29361407 | 0.74 | PDK1 (0.51) | MAPTKDRKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415345-A | Broad spectrum influenza inhibitor based on pyridazinone | 豪夫迈·罗氏有限公司 | 2019-03-01 | — | — | CN | disclosed |