Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GOT1 | P17174 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27830129 | 0.83 | ADORA2A (0.51) | TP53NPSR1NPC1ALDH1A1LMNA | |
| SCHEMBL28877285 | 0.81 | EGFR (0.55) | KDM4ETP53CYP3A4GOT1SMN1; SMN2 | |
| SCHEMBL29816494 | 0.81 | KDM4E (0.48) | KDM4ETP53CYP3A4GOT1SMN1; SMN2 | |
| SCHEMBL1268508 | 0.81 | KDM4E (0.48) | KDM4ETP53CYP3A4GOT1SMN1; SMN2 | |
| SCHEMBL28869366 | 0.80 | ACP1 (0.43) | KIF11KDM4ETP53CYP3A4GOT1 | |
| SCHEMBL28657632 | 0.79 | KDM4E (0.47) | KDM4ETP53CYP3A4GOT1SMN1; SMN2 | |
| SCHEMBL29361407 | 0.78 | PDK1 (0.51) | KDM4ETP53CYP3A4GOT1SMN1; SMN2 | |
| SCHEMBL30656055 | 0.78 | CYP1A2 (0.43) | KDM4ETP53CYP3A4GOT1SMN1; SMN2 | |
| SCHEMBL27973696 | 0.78 | ALDH1A1 (0.50) | KDM4ETP53CYP3A4GOT1SMN1; SMN2 | |
| SCHEMBL28167414 | 0.78 | NPC1 (0.43) | TNKSTNKS2KDM4ETP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |