Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | GOT1 | P17174 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268508 | 0.85 | KDM4E (0.48) | EGFRKDRADORA2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29816494 | 0.85 | KDM4E (0.48) | EGFRKDRADORA2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28657632 | 0.83 | KDM4E (0.47) | EGFRKDRADORA2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28167414 | 0.82 | NPC1 (0.43) | KDRADORA2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL27415412 | 0.82 | PDK1 (0.51) | EGFRKDRADORA2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29361407 | 0.82 | PDK1 (0.51) | EGFRKDRADORA2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27973696 | 0.82 | ALDH1A1 (0.50) | ADORA2ASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL27973695 | 0.82 | LMNA (0.46) | EGFRKDRSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL30656055 | 0.82 | CYP1A2 (0.43) | EGFRKDRSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL28877249 | 0.81 | KIF11 (0.44) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |