Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28957185 | 0.86 | LMNA (0.50) | LMNAMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL91621 | 0.86 | ALDH1A1 (0.52) | LMNAMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL29077276 | 0.84 | MAPT (0.46) | LMNAMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL29077275 | 0.84 | RAB9A (0.52) | LMNAMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL10906062 | 0.80 | ATM (0.59) | MAPTALDH1A1GRM5HPGDNPC1 | |
| SCHEMBL30566762 | 0.80 | ATM (0.59) | MAPTALDH1A1GRM5HPGDNPC1 | |
| SCHEMBL102749 | 0.80 | CNR1 (0.46) | LMNAMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL29077248 | 0.77 | NOTUM (0.39) | LMNAMAPTALDH1A1L3MBTL1HPGD | |
| SCHEMBL14363629 | 0.77 | CASP3 (0.49) | LMNAMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL30566771 | 0.77 | NOTUM (0.39) | LMNAMAPTALDH1A1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | claimed |
| CN-115093377-B | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | disclosed |