Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28870746

Cc1ncc(CN)c(N)n1.S

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.61
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 2/20 0.45
CYP1A2 P05177 1/20 0.45
TSHR P16473 1/20 0.45
TKT P29401 5/20 0.44
HSP90AA1 P07900 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL478879 0.98 LMNA (0.63) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL29895545 0.98 LMNA (0.63) LMNAKDM4EALDH1A1CYP1A2TSHR
Hydrochloric Acid SCHEMBL479404 0.96 LMNA (0.61) LMNAKDM4EALDH1A1CYP1A2TSHR
Bicarbonate SCHEMBL9320107 0.89 LMNA (0.54) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL27959821 0.82 LMNA (0.59) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL23748348 0.81 LMNA (0.63) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL12346332 0.81 LMNA (0.63) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL16015176 0.79 LMNA (0.61) LMNAKDM4EALDH1A1CYP1A2TSHR
SCHEMBL479344 0.79 LMNA (0.61) LMNAKDM4EALDH1A1TKTHSP90AA1
SCHEMBL23748342 0.79 LMNA (0.61) LMNAKDM4EALDH1A1CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109467553-A A kind of method of purification and vitamin B1 synthetic method of formyl pyrimidine 江苏兄弟维生素有限公司 2019-03-15 CN disclosed