Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.47 |
| ▸ | PDE4A | P27815 | 8/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28870890 | 0.95 | PDE4B (0.53) | HIF1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL27529057 | 0.83 | CA12 (0.53) | — | |
| SCHEMBL4632439 | 0.79 | PDE4D (0.42) | HIF1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL28073562 | 0.77 | PTGS1 (0.58) | — | |
| SCHEMBL17397335 | 0.76 | POLB (0.55) | HIF1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL24967198 | 0.76 | THRA (0.42) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7417740 | 0.76 | PDE4B (0.50) | HIF1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8684352 | 0.76 | PDE5A (0.50) | HIF1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL28133908 | 0.74 | PARP15 (0.47) | HIF1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6767181 | 0.74 | TRPA1 (0.53) | HIF1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209848-B | Cyclopentane-containing cinnamamide derivative with neuroprotective activity and preparation method thereof | 中山大学 | 2022-10-25 | — | — | CN | disclosed |