Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29967918 | 1.00 | MAPT (0.48) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL28957421 | 0.92 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL20561440 | 0.78 | MAPT (0.75) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL9754832 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1CHEK1 | |
| SCHEMBL28871222 | 0.75 | GRIN1 (0.46) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL29968491 | 0.75 | GRIN1 (0.46) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL28871299 | 0.75 | POLB (0.44) | ALDH1A1PARP1 | |
| SCHEMBL29968130 | 0.75 | POLB (0.44) | ALDH1A1PARP1 | |
| SCHEMBL20297892 | 0.74 | POLB (0.43) | MAPTKDM4EALDH1A1SMN1; SMN2CHEK1 | |
| SCHEMBL31029252 | 0.74 | DDAH1 (0.53) | ALDH1A1SMN1; SMN2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |