Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871299 | 1.00 | POLB (0.44) | POLBGRM2PARP1ALDH1A1GSK3B | |
| SCHEMBL9754832 | 0.90 | ALDH1A1 (0.46) | POLBGRM2ALDH1A1 | |
| SCHEMBL6810627 | 0.88 | POLB (0.43) | POLBPARP1ALDH1A1 | |
| SCHEMBL28379367 | 0.84 | POLB (0.44) | POLB | |
| SCHEMBL31029252 | 0.83 | DDAH1 (0.53) | GRM2ALDH1A1 | |
| SCHEMBL28871267 | 0.83 | DDAH1 (0.53) | GRM2ALDH1A1 | |
| SCHEMBL31546228 | 0.83 | POLB (0.46) | POLB | |
| SCHEMBL6755252 | 0.83 | MGAM (0.45) | POLBALDH1A1 | |
| SCHEMBL3245583 | 0.81 | PDE10A (0.54) | POLBPARP1ALDH1A1 | |
| SCHEMBL28957421 | 0.78 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |