SCHEMBL2887187

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1165100	0.84	CHRNB2 (0.50)	CHRNB2CHRNA4ALDH1A1KDM4EOPRM1
	SCHEMBL28810661	0.82	KDM4E (0.42)	CHRNB2CHRNA4ALDH1A1KDM4EOPRM1
	SCHEMBL28892305	0.79	NR3C2 (0.49)	CHRNB2CHRNA4ALDH1A1NR3C2
	SCHEMBL29728033	0.77	ALDH1A1 (0.37)	ALDH1A1LMNA
	SCHEMBL2886113	0.77	PARP1 (0.34)	NR3C2
	SCHEMBL2892825	0.75	KCNH2 (0.42)	KDM4EOPRM1OPRL1LMNA
	SCHEMBL487449	0.75	CA1 (0.30)	—
	SCHEMBL28691222	0.74	NR3C2 (0.33)	NR3C2
	SCHEMBL14995922	0.70	PDE3B (0.33)	NR3C2
	SCHEMBL12888668	0.70	CHRNB2 (0.67)	CHRNB2CHRNA4ALDH1A1KDM4EOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.