Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7335796 | 0.98 | ALDH1A1 (0.52) | ALDH1A1PKMCHRM2NPC1MAPT | |
| SCHEMBL7346729 | 0.91 | ALDH1A1 (0.61) | ALDH1A1PKMCHRM2NPC1MAPT | |
| Hydrochloric Acid SCHEMBL7034100 | 0.89 | ALDH1A1 (0.59) | ALDH1A1PKMCHRM2NPC1MAPT | |
| SCHEMBL8349970 | 0.83 | ACHE (0.62) | ALDH1A1PKMCHRM2NPC1MAPT | |
| SCHEMBL7484129 | 0.83 | LTA4H (0.67) | ALDH1A1PKMNPC1RAB9AMEN1 | |
| SCHEMBL8415551 | 0.82 | HTT (0.58) | ALDH1A1PKMCHRM2MEN1GAA | |
| SCHEMBL2029638 | 0.81 | CHRM2 (0.63) | ALDH1A1PKMCHRM2NPC1MAPT | |
| SCHEMBL14137298 | 0.81 | ALDH1A1 (0.55) | ALDH1A1PKMCHRM2NPC1MAPT | |
| SCHEMBL8673489 | 0.79 | ALDH1A1 (0.53) | ALDH1A1PKMCHRM2NPC1MAPT | |
| SCHEMBL121529 | 0.78 | CHRM2 (0.70) | ALDH1A1PKMCHRM2GAAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753858-B | Heterocyclic compound and p27Kip1Decomposing inhibitor | ASKA制药株式会社 | 2019-04-30 | — | — | CN | disclosed |