Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ELANE | P08246 | 8/20 | 0.56 |
| ▸ | ACLY | P53396 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | CTSG | P08311 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16226428 | 0.95 | MEN1 (0.63) | EPHX2MEN1KMT2ANPC1MAPT | |
| SCHEMBL28872286 | 0.86 | EPHX2 (0.60) | EPHX2MEN1KMT2ANPC1MAPT | |
| SCHEMBL23198975 | 0.84 | EPHX2 (0.65) | EPHX2MEN1KMT2ANPC1MAPT | |
| SCHEMBL29709367 | 0.81 | EPHX2 (0.70) | EPHX2MEN1KMT2ANPC1MAPT | |
| SCHEMBL31441199 | 0.81 | EPHX2 (0.64) | EPHX2MEN1KMT2ANPC1MAPT | |
| SCHEMBL29066488 | 0.78 | ACLY (0.52) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL17867452 | 0.78 | MEN1 (0.61) | EPHX2MEN1KMT2ANPC1MAPT | |
| SCHEMBL28872293 | 0.77 | RAB9A (0.59) | EPHX2MEN1KMT2ANPC1MAPT | |
| SCHEMBL31441205 | 0.76 | MAPT (1.00) | EPHX2MEN1KMT2ANPC1MAPT | |
| SCHEMBL1426486 | 0.76 | MAPT (1.00) | EPHX2MEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115245533-B | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | claimed |
| WO-2022228095-A1 | APPLICATION OF PRISMATOMERIS CONNATA Y. Z. RUAN ROOT EXTRACT IN PREPARATION OF MEDICINE FOR TREATING PULMONARY FIBROSIS | 中国医学科学院药物研究所 | 2022-11-03 | — | — | WO | claimed |
| CN-115245533-A | Application of south mountain flower root extract in pulmonary fibrosis treatment | 中国医学科学院药物研究所 | 2022-10-28 | — | — | CN | claimed |
| CN-116585295-A | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-08-15 | — | — | CN | disclosed |
| CN-115245533-B | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022228095-A1 | APPLICATION OF PRISMATOMERIS CONNATA Y. Z. RUAN ROOT EXTRACT IN PREPARATION OF MEDICINE FOR TREATING PULMONARY FIBROSIS | 中国医学科学院药物研究所 | 2022-11-03 | — | — | WO | disclosed |
| CN-115245533-A | Application of south mountain flower root extract in pulmonary fibrosis treatment | 中国医学科学院药物研究所 | 2022-10-28 | — | — | CN | disclosed |