Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.42 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022539 | 0.83 | MAPT (0.42) | CDYL2CDYLPGRMAPTMEN1 | |
| SCHEMBL2332856 | 0.83 | MAPT (0.42) | CDYL2CDYLPGRMAPTMEN1 | |
| SCHEMBL23835717 | 0.76 | MAPT (0.56) | CDYL2CDYLPGRMAPTTSHR | |
| SCHEMBL24020000 | 0.76 | MAPT (0.56) | CDYL2CDYLPGRMAPTTSHR | |
| SCHEMBL24447559 | 0.72 | CDYL2 (0.47) | CDYL2CDYLPGRMAPTMEN1 | |
| SCHEMBL1899980 | 0.71 | PGR (0.40) | PGRMEN1KMT2AIDO1TDO2 | |
| SCHEMBL24754591 | 0.70 | PGR (0.72) | CDYL2CDYLPGRMAPTMEN1 | |
| SCHEMBL2986303 | 0.70 | PGR (0.72) | CDYL2CDYLPGRMAPTMEN1 | |
| SCHEMBL16977576 | 0.68 | IDO1 (0.62) | CDYL2CDYLPGRMAPTTSHR | |
| SCHEMBL24112733 | 0.68 | PGR (0.69) | CDYL2CDYLPGRMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645887-B2 | 2-(5-iodo-2-oxo-2,3-dihydro-1H-indol-1-yl)acetamide; epilepsy, epileptogenesis, seizure disorders and convulsion; 2-(5-chloro-2-oxo-2,3-dhydro-1H-indol-1-yl)-N-[6-(hydroxymethyl)cyclohex-3-en-1-yl]acetamide | UCB PHARMA, S.A. (BE) | 2010-01-12 | — | — | US | claimed |