Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753448 | 1.00 | CYP4F2 (0.41) | CYP4F2CYP4A11HPGDHTTCTSG | |
| SCHEMBL30753435 | 0.89 | LMNA (0.48) | CYP4F2CYP4A11CTSGCMA1ALDH1A1 | |
| SCHEMBL21715380 | 0.89 | LMNA (0.48) | CYP4F2CYP4A11CTSGCMA1ALDH1A1 | |
| SCHEMBL28873178 | 0.82 | CYP4F2 (0.52) | CYP4F2CYP4A11ALDH1A1MEN1KMT2A | |
| SCHEMBL21715429 | 0.81 | HPGD (0.40) | CYP4F2CYP4A11HPGDHTTALDH1A1 | |
| SCHEMBL30753436 | 0.81 | HPGD (0.40) | CYP4F2CYP4A11HPGDHTTALDH1A1 | |
| SCHEMBL14721724 | 0.80 | ALDH1A1 (0.48) | CYP4F2CYP4A11HPGDHTTALDH1A1 | |
| SCHEMBL21715447 | 0.80 | DRD2 (0.45) | CYP4F2CYP4A11HPGDCTSGCMA1 | |
| SCHEMBL30753446 | 0.80 | DRD2 (0.45) | CYP4F2CYP4A11HPGDCTSGCMA1 | |
| SCHEMBL3407322 | 0.80 | CTSG (0.48) | HPGDHTTCTSGCMA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112789035-B | Benzocycloheptene analogues and related compounds having activity as anticancer agents | 贝勒大学 | 2024-02-09 | — | — | CN | disclosed |
| EP-3836910-A1 | BENZOSUBERENE ANALOGUES AND RELATED COMPOUNDS WITH ACTIVITY AS ANTICANCER AGENTS | Baylor University (US) | 2021-06-23 | — | — | EP | disclosed |
| CN-112789035-A | Benzocycloheptene analogs and related compounds having activity as anticancer agents | 贝勒大学 | 2021-05-11 | — | — | CN | disclosed |
| US-10807932-B2 | Benzosuberene analogues and related compounds with activity as anticancer agents | BAYLOR UNIVERSITY (US) | 2020-10-20 | — | — | US | disclosed |
| US-10807932-B2 | Benzosuberene analogues and related compounds with activity as anticancer agents | BAYLOR UNIVERSITY (US) | 2020-10-20 | — | — | US | disclosed |
| US-20200055805-A1 | BENZOSUBERENE ANALOGUES AND RELATED COMPOUNDS WITH ACTIVITY AS ANTICANCER AGENTS | BAYLOR UNIVERSITY (US) | 2020-02-20 | — | — | US | disclosed |
| WO-2020037209-A1 | BENZOSUBERENE ANALOGUES AND RELATED COMPOUNDS WITH ACTIVITY AS ANTICANCER AGENTS | BAYLOR UNIVERSITY (US) | 2020-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055805-A1 | BENZOSUBERENE ANALOGUES AND RELATED COMPOUNDS WITH ACTIVITY AS ANTICANCER AGENTS | TUBB1, TUBB3, TUBB | CYP4F2 3707/4885CYP4A11 2939/4885HPGD 1485/4885 |
| US-10807932-B2 | Benzosuberene analogues and related compounds with activity as anticancer agents | TUBB1, TUBB3, TUBB | CYP4F2 3707/4885CYP4A11 2939/4885HPGD 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.