SCHEMBL28873235

SCHEMBL28873235

CO[SiH](OC)c1c(-c2ccccc2)cccc1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.39
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
ALDH1A1 P00352 5/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
BCL2L1 Q07817 1/20 0.38
CYP2A6 P11509 1/20 0.38
MAPK1 P28482 1/20 0.38
MAPT P10636 2/20 0.37
MITF O75030 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
PTGS2 P35354 1/20 0.35
MEN1 O00255 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
ADRB2 P07550 1/20 0.35
BACE1 P56817 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295619 0.75 BACE1 (0.44) PDCD1CD274ALDH1A1HSD17B10HPGD
Methoxymethane SCHEMBL27842914 0.73 ALDH1A1 (0.50) DPP4PDCD1CD274ALDH1A1HSD17B10
SCHEMBL13385087 0.70 PDE4B (0.48) PDCD1CD274ALDH1A1HSD17B10HPGD
SCHEMBL21722359 0.68 PDCD1 (0.37) DPP4PDCD1CD274ALDH1A1HSD17B10
SCHEMBL31290744 0.66 ALDH1A1 (0.53) DPP4PDCD1CD274ALDH1A1HSD17B10
Benzene SCHEMBL28035419 0.66 ALDH1A1 (0.61) DPP4ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL21447 0.66 ALDH1A1 (0.61) DPP4ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL2361430 0.66 ALDH1A1 (0.61) DPP4ALDH1A1HSD17B10HPGDBCL2L1
Biphenyl SCHEMBL1048244 0.66 ALDH1A1 (0.53) ALDH1A1HSD17B10BCL2L1MAPK1MAPT
SCHEMBL25785668 0.66 PDCD1 (0.64) PDCD1CD274ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109716544-A LED Encapulant composition 日产化学株式会社 2019-05-03 CN disclosed