SCHEMBL28874019

SCHEMBL28874019

COCc1ccccc1.c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
IDO1 P14902 1/20 0.43
TP53 P04637 1/20 0.42
ALDH1A1 P00352 4/20 0.41
MAPT P10636 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
AGXT P21549 1/20 0.41
MAOB P27338 1/20 0.40
CHRM2 P08172 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
CHRM1 P11229 1/20 0.39
DRD1 P21728 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279614 0.94 ALDH1A1 (0.45) TSHRIDO1TP53ALDH1A1MAPT
SCHEMBL279615 0.94 ALDH1A1 (0.45) TSHRIDO1TP53ALDH1A1MAPT
SCHEMBL10330363 0.88 IDO1 (0.46) IDO1ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL19675175 0.88 TSHR (0.40) TSHRIDO1TP53ALDH1A1MAPT
SCHEMBL13681219 0.88 TSHR (0.40) TSHRIDO1TP53ALDH1A1MAPT
SCHEMBL794 0.86
SCHEMBL12960568 0.85 LTA4H (0.52) IDO1TDP1L3MBTL1AGXTFAAH
SCHEMBL279197 0.84 IDO1 (0.50) TSHRIDO1AGXTFAAHMGLL
SCHEMBL279357 0.84 APP (0.37) TSHRIDO1TP53ALDH1A1MAPT
Hydrochloric Acid SCHEMBL9981027 0.84 TSHR (0.57) TSHRIDO1TP53ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776392-A A kind of carbazole-N- base diphenylethyllene triphenylamine derivative hole mobile material and preparation method thereof 天津大学 2019-05-21 CN disclosed