Phenol

Phenol

SCHEMBL28874154

CC(C)(C)c1cccc(-c2ccccc2)c1.Oc1ccccc1

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.62
RXRB P28702 2/20 0.62
KIF11 P52732 1/20 0.59
HSD17B1 P14061 3/20 0.50
HSD17B2 P37059 3/20 0.50
ESR1 P03372 4/20 0.48
ESR2 Q92731 3/20 0.48
CYP3A4 P08684 2/20 0.48
ALDH1A1 P00352 1/20 0.48
CYP2C9 P11712 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
OPRD1 P41143 2/20 0.48
OPRM1 P35372 1/20 0.48
OPRK1 P41145 1/20 0.48
PTPN1 P18031 2/20 0.47
PTPN5 P54829 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1513832 0.90 RXRA (0.64) RXRARXRBKIF11HSD17B1HSD17B2
SCHEMBL3816403 0.90 RXRA (0.64) RXRARXRBKIF11HSD17B1HSD17B2
SCHEMBL779683 0.90 KIF11 (0.70) RXRARXRBKIF11CYP3A4ALDH1A1
SCHEMBL15394543 0.88 KIF11 (0.58) RXRARXRBKIF11HSD17B1HSD17B2
Phenol SCHEMBL27853938 0.88 ESR1 (0.57) RXRARXRBKIF11ESR1ESR2
SCHEMBL25693197 0.88 KIF11 (0.68) RXRARXRBKIF11CYP3A4ALDH1A1
Phenol SCHEMBL7192832 0.86 ALDH1A1 (0.54) RXRARXRBKIF11HSD17B1HSD17B2
SCHEMBL27659191 0.85 KIF11 (0.76) RXRARXRBKIF11ALDH1A1OPRD1
SCHEMBL5547288 0.83 KIF11 (0.72) RXRARXRBKIF11ALDH1A1OPRD1
SCHEMBL30023786 0.83 KIF11 (0.72) RXRARXRBKIF11ALDH1A1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109942362-A Include the steps that the ethylene dimerization method for handling reaction effluent IFP 新能源公司 2019-06-28 CN disclosed