Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.64 |
| ▸ | RXRB | P28702 | 2/20 | 0.64 |
| ▸ | ESR1 | P03372 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KIF11 | P52732 | 1/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.57 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | BCR | P11274 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513832 | 1.00 | RXRA (0.64) | RXRARXRBESR1MEN1KMT2A | |
| Phenol SCHEMBL28874154 | 0.90 | RXRA (0.62) | RXRARXRBESR1MEN1KMT2A | |
| SCHEMBL11223777 | 0.88 | ESR1 (0.68) | RXRARXRBESR1MEN1KMT2A | |
| SCHEMBL27659191 | 0.87 | KIF11 (0.76) | RXRARXRBKIF11HDAC4HDAC2 | |
| SCHEMBL15394543 | 0.86 | KIF11 (0.58) | RXRARXRBESR1KIF11HSD17B1 | |
| SCHEMBL17105790 | 0.85 | KIF11 (0.68) | RXRARXRBKIF11HSD17B2HDAC4 | |
| SCHEMBL5547288 | 0.85 | KIF11 (0.72) | RXRARXRBKIF11HDAC4HDAC2 | |
| SCHEMBL30023786 | 0.85 | KIF11 (0.72) | RXRARXRBKIF11HDAC4HDAC2 | |
| SCHEMBL12004653 | 0.85 | ESR1 (0.62) | RXRARXRBESR1MEN1KMT2A | |
| SCHEMBL21084882 | 0.83 | ESR1 (0.66) | RXRARXRBESR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375461-B1 | DIPHENOL AND PROCESS FOR PRODUCING THE SAME | HONSHU CHEMICAL IND (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6872858-B2 | Diphenol and process for producing the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20040049086-A1 | Diphenol and process for producing the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1375461-A1 | DIPHENOL AND PROCESS FOR PRODUCING THE SAME | Honshu Chemical Industry Co. Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049086-A1 | Diphenol and process for producing the same | CYP1A1, AHR, CYP2E1 | RXRA 1837/4885RXRB 2406/4885ESR1 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.