Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14793650 | 0.88 | ALDH1A1 (0.59) | GAAMAPTALDH1A1HSP90AA1ELANE | |
| SCHEMBL23392549 | 0.83 | GAA (0.58) | GAAMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL23928486 | 0.81 | RAB9A (0.61) | GAAMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL11684865 | 0.81 | ALDH1A1 (0.59) | GAAMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL3273659 | 0.80 | GAA (0.69) | GAAMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL4413307 | 0.80 | GAA (0.69) | GAAMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL13345208 | 0.80 | GAA (0.69) | GAAMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL28874996 | 0.79 | MEN1 (0.60) | GAAMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL19652417 | 0.78 | RAB9A (0.68) | GAAMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL12670648 | 0.78 | RAB9A (0.68) | GAAMAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260104-B | Preparation method of fullerene tetrahydropyridazine compound | 合肥学院 | 2023-10-27 | — | — | CN | claimed |
| CN-115260104-A | Preparation method of fullerene tetrahydropyridazine compound | 合肥学院 | 2022-11-01 | — | — | CN | claimed |
| CN-115260104-B | Preparation method of fullerene tetrahydropyridazine compound | 合肥学院 | 2023-10-27 | — | — | CN | disclosed |
| CN-115260104-A | Preparation method of fullerene tetrahydropyridazine compound | 合肥学院 | 2022-11-01 | — | — | CN | disclosed |