Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.61 |
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12670647 | 0.95 | TSHR (0.59) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4413307 | 0.82 | GAA (0.69) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13345208 | 0.82 | GAA (0.69) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3273659 | 0.82 | GAA (0.69) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23392549 | 0.82 | GAA (0.58) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL28874995 | 0.81 | GAA (0.59) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23928652 | 0.81 | FAAH (0.54) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL12670648 | 0.80 | RAB9A (0.68) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL19652417 | 0.80 | RAB9A (0.68) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11684865 | 0.80 | ALDH1A1 (0.59) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548875-B2 | Inhibitor compounds for male contraception | UNIVERSITY OF WASHINGTON (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | UNIVERSITY OF WASHINGTON (US) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | ALDH1A1, ALDH3A1, ALDH16A1 | RAB9A 4266/4885MAPT 4083/4885SMN1; SMN2 2873/4885 |
| US-11548875-B2 | Inhibitor compounds for male contraception | ALDH1A1, ALDH3A1, ALDH16A1 | RAB9A 4266/4885MAPT 4083/4885SMN1; SMN2 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.