Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393327 | 0.88 | POLB (0.54) | MEN1KMT2AANO1POLBPTGDR2 | |
| SCHEMBL27551256 | 0.83 | IDO1 (0.50) | MEN1KMT2APOLBCES2IDO1 | |
| SCHEMBL5435480 | 0.80 | IDO1 (0.42) | MEN1KMT2AANO1IDO1 | |
| SCHEMBL3135089 | 0.79 | RXRA (0.53) | MEN1KMT2AANO1CES2POLQ | |
| SCHEMBL5438219 | 0.79 | IDO1 (0.41) | MEN1KMT2AANO1IDO1POLQ | |
| SCHEMBL1988262 | 0.79 | TYR (0.46) | MEN1KMT2AANO1IDO1 | |
| SCHEMBL12806555 | 0.78 | ESR1 (0.48) | MEN1KMT2AANO1CES2IDO1 | |
| SCHEMBL27647753 | 0.78 | CA3 (0.45) | POLBCHRNA7 | |
| SCHEMBL28234868 | 0.78 | TAS2R14 (0.40) | MEN1KMT2APTGDR2CES2FFAR4 | |
| SCHEMBL27643679 | 0.78 | ALDH1A1 (0.45) | MEN1KMT2AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110049973-A | 1, 4-diphenyl-1H-imidazole and 2, 4-diphenyl thiazole derivatives, and preparation method and application thereof | 南方医科大学 | 2019-07-23 | — | — | CN | disclosed |