Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28763974 | 0.85 | ALDH1A1 (0.46) | LMNAALDH1A1HSD17B10RAD52SMN1; SMN2 | |
| P-Xylene SCHEMBL11399447 | 0.78 | LMNA (0.54) | LMNAL3MBTL1ALDH1A1HSD17B10RAD52 | |
| SCHEMBL6914520 | 0.77 | KMT2A (0.35) | LMNAL3MBTL1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL19454527 | 0.77 | ALDH1A1 (0.37) | LMNAALDH1A1HSD17B10SMN1; SMN2TDP1 | |
| SCHEMBL20906472 | 0.75 | ACHE (0.42) | LMNAALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL20921311 | 0.75 | ACHE (0.42) | LMNAALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL11219851 | 0.75 | HTT (0.40) | LMNAL3MBTL1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11375556 | 0.74 | KMT2A (0.47) | L3MBTL1ALDH1A1HSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL254515 | 0.73 | ALDH1A1 (0.37) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| P-Xylene SCHEMBL8770845 | 0.72 | LMNA (0.48) | LMNAL3MBTL1ALDH1A1HSD17B10RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041236-A | The synthetic method of thio-ether type compounds | 天津师范大学 | 2019-07-23 | — | — | CN | disclosed |