Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28153684 | 0.77 | KDM4E (0.43) | MEN1KMT2ACYP2C19ALDH1A1MAPT | |
| SCHEMBL27807785 | 0.75 | KDM4E (0.39) | KCNH2PRMT1MEN1KMT2ALMNA | |
| SCHEMBL21358025 | 0.74 | GABRA1 (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8683211 | 0.72 | GABRA1 (0.37) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10321771 | 0.70 | MET (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL26725957 | 0.70 | KMT2A (0.46) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL27927247 | 0.70 | MAPT (0.37) | KCNH2MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL2596737 | 0.70 | ALDH1A1 (0.41) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL2068719 | 0.69 | MEN1 (0.45) | MEN1KMT2ACA1CA2LMNA | |
| SCHEMBL5376069 | 0.69 | TLR7 (0.45) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117193-B | New Hete rocyclic derivatives and its application in neurogenic disease treatment | 诺华股份有限公司 | 2019-09-13 | — | — | CN | disclosed |