Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | IL1RN | P18510 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675156 | 0.79 | KEAP1 (0.52) | KEAP1ARHPGDCA1CA2 | |
| SCHEMBL28657038 | 0.78 | CA1 (0.55) | KEAP1ARHPGDCA1CA2 | |
| SCHEMBL11868146 | 0.73 | KEAP1 (0.47) | KEAP1ARHTTCA1CA2 | |
| SCHEMBL30797878 | 0.73 | CA2 (0.44) | KEAP1ARHPGDHTTCA1 | |
| SCHEMBL675949 | 0.72 | KEAP1 (0.58) | KEAP1HPGDHTTCA1CA2 | |
| SCHEMBL2016598 | 0.72 | KEAP1 (0.56) | KEAP1HPGDHTTCA1CA2 | |
| SCHEMBL5130306 | 0.71 | CA2 (0.42) | KEAP1HPGDCA1CA2IL1RN | |
| SCHEMBL9136815 | 0.71 | NPC1 (0.49) | HPGDCA1CA2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28137064 | 0.71 | KEAP1 (0.56) | KEAP1HPGDHTTCA1CA2 | |
| SCHEMBL28779160 | 0.70 | RAB9A (0.49) | ARHPGDHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105935-A | A kind of high strength multifunctional blocking agent | 陕西鼎和源瑞环境工程有限公司 | 2019-08-09 | — | — | CN | disclosed |