Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19313223 | 0.83 | MAPT (0.62) | HDAC6MAPTRXFP1HDAC1HDAC2 | |
| SCHEMBL19612671 | 0.82 | NAAA (0.56) | HDAC6MAPTRXFP1FAAHNAAA | |
| SCHEMBL19612566 | 0.81 | NAAA (0.55) | HDAC6MAPTRXFP1FAAHCES1 | |
| SCHEMBL9662576 | 0.81 | NAAA (0.55) | HDAC6MAPTRXFP1HDAC1HDAC2 | |
| SCHEMBL19612745 | 0.81 | NAAA (0.55) | HDAC6MAPTRXFP1HDAC1HDAC2 | |
| SCHEMBL19612688 | 0.80 | NAAA (0.56) | FAAHNAAA | |
| SCHEMBL5793035 | 0.79 | MAPT (0.71) | HDAC6MAPTRXFP1HDAC1ACHE | |
| SCHEMBL376652 | 0.79 | MAPT (0.55) | HDAC6MAPTRXFP1HDAC1ACHE | |
| SCHEMBL15007876 | 0.79 | MAPT (0.55) | HDAC6MAPTRXFP1HDAC1ACHE | |
| SCHEMBL3250759 | 0.79 | MAPT (0.71) | HDAC6MAPTRXFP1HDAC1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074788-B | Substituted heterocyclic derivatives, preparation method and application thereof | 厦门大学 | 2019-09-20 | — | — | CN | disclosed |