Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.62 |
| ▸ | FAAH | O00519 | 3/20 | 0.61 |
| ▸ | CES1 | P23141 | 3/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253249 | 1.00 | MAPT (0.71) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL7768077 | 1.00 | MAPT (0.71) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL7883758 | 1.00 | MAPT (0.71) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL5793035 | 1.00 | MAPT (0.71) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL9664005 | 1.00 | MAPT (0.71) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL9664667 | 1.00 | MAPT (0.71) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL384438 | 0.98 | MAPT (0.68) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL8772423 | 0.94 | MAPT (0.82) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL61491 | 0.92 | HDAC1 (0.69) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL27538484 | 0.90 | HDAC1 (0.67) | MAPTRXFP1HDAC1HDAC2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4692061-A1 | LOW-MOLECULAR-WEIGHT COMPOUND HAVING CEREBLON-BINDING ACTIVITY, AND USE THEREOF | Aevis Bio, Inc. (KR) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024205319-A1 | LOW-MOLECULAR-WEIGHT COMPOUND HAVING CEREBLON-BINDING ACTIVITY, AND USE THEREOF | 주식회사 아이비스바이오 | 2024-10-03 | — | — | WO | disclosed |
| US-10174015-B2 | Substituted heterocyclic derivative, preparation method and use thereof | XIAMEN UNIVERSITY (CN) | 2019-01-08 | — | — | US | disclosed |
| US-20170334896-A1 | Substituted Heterocyclic Derivative, Preparation Method And Use Thereof | XIAMEN UNIVERSITY (CN) | 2017-11-23 | — | — | US | disclosed |
| EP-1925617-B1 | HETEROCYCLIC COMPOUND, AND PRODUCTION PROCESS AND USE THEREOF | ASKA PHARM CO LTD (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-8193356-B2 | Heterocycle compound, and production process and application thereof | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2012-06-05 | — | — | US | disclosed |
| EP-2029601-B1 | PYRIDOPYRIMIDINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-06-02 | — | — | EP | disclosed |
| US-7572801-B2 | Pyridopyrimidinone derivatives which are HM74A agonists | HOFFMANN-LA ROCHE INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-20090131467-A1 | Heterocycle Compound, and Production Process and Application Thereof | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-2029601-A1 | PYRIDOPYRIMIDINONE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| US-20070275987-A1 | Novel pyridopyprimidinone derivatives which are HM74A agonists | HOFFMAN-LA ROCHE INC | 2007-11-29 | — | — | US | disclosed |
| EP-0569386-B1 | BRIDGED CYCLIC KETAL DERIVATIVES | GLAXO GROUP LTD (GB) | 1996-09-25 | — | — | EP | disclosed |
| US-5405989-A | Controlling house dust mites | SUMITOMO CHEMICAL CO., LTD. (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0597660-A2 | Propargyl ester compounds, acaricides containing the same as an active ingredient and an acaricidal method | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-05-18 | — | — | EP | disclosed |
| EP-0569386-A1 | BRIDGED CYCLIC KETAL DERIVATIVES. | GLAXO GROUP LTD (GB) | 1993-11-18 | — | — | EP | disclosed |
| EP-0497091-A1 | Bridged cyclic ketal derivatives | GLAXO GROUP LIMITED (GB) | 1992-08-05 | — | — | EP | disclosed |
| WO-1992012159-A1 | BRIDGED CYCLIC KETAL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1992-07-23 | — | — | WO | disclosed |
| EP-0273451-B1 | LIPOXYGENASE INHIBITORY COMPOUNDS | Bristol-Myers Squibb Company (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4861798-A | Lipoxygenase inhibitory compounds | BRISTOL-MYERS COMPANY (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0273451-A2 | Lipoxygenase inhibitory compounds | Bristol-Myers Squibb Company (US) | 1988-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334896-A1 | Substituted Heterocyclic Derivative, Preparation Method And Use Thereof | FAAH, NAAA, FAAH2 | MAPT 2676/4885RXFP1 2509/4885HDAC1 317/4885 |
| US-20090131467-A1 | Heterocycle Compound, and Production Process and Application Thereof | PDE3B, PDE4B, PDE7A | MAPT 4865/4885RXFP1 1826/4885HDAC1 194/4885 |
| US-20070275987-A1 | Novel pyridopyprimidinone derivatives which are HM74A agonists | GPR119, HCAR1, GPR84 | MAPT 4450/4885RXFP1 171/4885HDAC1 2823/4885 |
| US-10174015-B2 | Substituted heterocyclic derivative, preparation method and use thereof | DHPS, CYP3A5, CYP3A4 | MAPT 3746/4885RXFP1 4818/4885HDAC1 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.