Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | KLK1 | P06870 | 2/20 | 0.40 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877400 | 0.87 | KMT2A (0.55) | LMNAKMT2AMEN1PKMNPC1 | |
| SCHEMBL30032488 | 0.82 | TIMP3 (0.50) | LMNAMAPTKMT2AMEN1POLB | |
| SCHEMBL23796526 | 0.82 | TIMP3 (0.50) | LMNAMAPTKMT2AMEN1POLB | |
| SCHEMBL28877371 | 0.81 | KMT2A (0.48) | LMNAMAPTKMT2APLAUMEN1 | |
| SCHEMBL23796657 | 0.80 | MEN1 (0.47) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL28957929 | 0.79 | TOP1 (0.44) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL28877397 | 0.78 | GAA (0.48) | LMNAMAPTKMT2APLAUMEN1 | |
| SCHEMBL28877451 | 0.78 | TOP1 (0.45) | LMNAMAPTKMT2AMEN1PKM | |
| SCHEMBL23796919 | 0.77 | NR1H4 (0.52) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL23796747 | 0.76 | ALDH1A1 (0.44) | LMNAMAPTKMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |