Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GFER | P55789 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877472 | 0.87 | KMT2A (0.46) | TOP1ALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL23796526 | 0.79 | TIMP3 (0.50) | TIMP3BCL2L1ALDH1A1GFERLMNA | |
| SCHEMBL30032488 | 0.79 | TIMP3 (0.50) | TIMP3BCL2L1ALDH1A1GFERLMNA | |
| SCHEMBL23796586 | 0.79 | TIMP3 (0.50) | TIMP3BCL2L1ALDH1A1GFERLMNA | |
| SCHEMBL28877392 | 0.79 | TOP1 (0.44) | TOP1CA1CA2CA7CA9 | |
| SCHEMBL28877498 | 0.78 | LMNA (0.44) | TOP1ALDH1A1LMNAPKMNPC1 | |
| SCHEMBL23796725 | 0.74 | BCL2 (0.46) | TIMP3BCL2L1ALDH1A1GFERLMNA | |
| SCHEMBL30031784 | 0.74 | BCL2 (0.46) | TIMP3BCL2L1ALDH1A1GFERLMNA | |
| SCHEMBL28957929 | 0.71 | TOP1 (0.44) | TOP1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28877400 | 0.71 | KMT2A (0.55) | ALDH1A1LMNAKDM4ETP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |